[Tyra Talk] 03/09/2024 Aging, locus coeruleus, and decision-making
大家總是說「越老越糊塗」，這是有腦科學依據的嗎？在本次演講中，陳香瑜博士將討論不同年齡層的腦部結構、功能差異，尤其聚焦在與動機、決策相關的藍斑核（locus coeruleus）。
|| 講者（Speaker）:
陳香瑜(Hsiang-Yu Chen)
Hsiang-Yu finished her Ph.D. at Dresden University of Technology. In her graduate studies, she used a multimodal approach including pupillometry assessment, MRI, and modeling to investigate decision-making and reward learning in aging. Her current research interests include PET and pupillometry studies to understand how age-related decline in the catecholaminergic functioning such as dopamine or norepinephrine may affect decision-making in old age and how it may be related to brain network activity or tau pathology.
|| 摘要（Abstract）:
The locus coeruleus (LC), which produces catecholamines (norepinephrine and dopamine), is one of the earliest brain regions to accumulate abnormal tau protein in Alzheimer’s disease. Relevant to cognition, the LC is a critical driver of affect, motivation, decision-making, and memory. However, the question about the nature of how age-related decline in the catecholamine system may alter decision-making is not well understood. In this talk, I will introduce the structure and neurochemical function of the LC on cognitive function and its association with aging. In addition, I will share my graduate studies, which conducted a multimodal approach, including pupillometry assessment, magnetic resonance imaging, and modeling, to investigate the associations between age differences in LC-related function and reward-based decision-making.
|| 研究領域（Field）:
自然科學、數學、統計
|| 研究子領域（Sub-field）:
老化腦科學
|| 主持人（Chair）:
|| 活動時間（ Event Time）:
03/09/2024 07:00 AM PST Pacific Time
03/09/2024 08:00 AM MST Mountain Time
03/09/2024 09:00 AM CST Central Time
03/09/2024 10:00 AM EST Eastern Time
03/09/2024 03:00 PM GMT England
03/09/2024 04:00 PM CET Berlin
03/09/2024 11:00 PM Taiwan
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https://linktr.ee/projecttyra